Revision as of 21:44, 24 November 2017 by en>JCW-CleanerBot(task, replaced: journal=Proc Natl Acad Sci U S A. → journal=Proc Natl Acad Sci U S A, added underlinked tag using AWB)
Ubiquitin specific peptidase 18 (USP18), also known as UBP43, is an enzyme that in human is encoded by the USP18 gene.[1] USP18 is a member of the deubiquitinating protease family of enzymes. It is thought to remove ISG15 adducts from a broad range of protein substrates, a process known as deISGylation.[1]
Li XL, Blackford JA, Judge CS, et al. (2000). "RNase-L-dependent destabilization of interferon-induced mRNAs. A role for the 2-5A system in attenuation of the interferon response". J. Biol. Chem. 275 (12): 8880–8. doi:10.1074/jbc.275.12.8880. PMID10722734.
Schwer H, Liu LQ, Zhou L, et al. (2000). "Cloning and characterization of a novel human ubiquitin-specific protease, a homologue of murine UBP43 (Usp18)". Genomics. 65 (1): 44–52. doi:10.1006/geno.2000.6148. PMID10777664.
Kang D, Jiang H, Wu Q, et al. (2001). "Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol RaSH". Gene. 267 (2): 233–42. doi:10.1016/S0378-1119(01)00384-5. PMID11313150.
Malakhov MP, Malakhova OA, Kim KI, et al. (2002). "UBP43 (USP18) specifically removes ISG15 from conjugated proteins". J. Biol. Chem. 277 (12): 9976–81. doi:10.1074/jbc.M109078200. PMID11788588.
Tokarz S, Berset C, La Rue J, et al. (2004). "The ISG15 isopeptidase UBP43 is regulated by proteolysis via the SCFSkp2 ubiquitin ligase". J. Biol. Chem. 279 (45): 46424–30. doi:10.1074/jbc.M403189200. PMID15342634.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID16189514.