Gallbladder cancer palliative treatment
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Palliative therapy in gallbladder cancer involves percutaneous transhepatic radiologic catheter bypass or endoscopically placed stents, standard external-beam radiation therapy, palliative surgery or standard chemotherapy.
Palliative Treatment
Palliative treatment options may include the following:
- The preferred approach to biliary obstruction is percutaneous transhepatic radiologic catheter bypass or endoscopically placed stents.[1]
- Standard external-beam radiation therapy can, on occasion, alleviate biliary obstruction in some patients and may supplement bypass procedures.
- Palliative surgery may relieve bile duct obstruction and is warranted when symptoms produced by biliary blockade (pruritus, hepatic dysfunction, and cholangitis) outweigh other symptoms from the cancer.
- Standard chemotherapy is usually not effective, though occasional patients may be palliated.[2]
References
- ↑ Baron TH (2001). "Expandable metal stents for the treatment of cancerous obstruction of the gastrointestinal tract". N Engl J Med. 344 (22): 1681–7. doi:10.1056/NEJM200105313442206. PMID 11386268.
- ↑ Hejna M, Pruckmayer M, Raderer M (1998). "The role of chemotherapy and radiation in the management of biliary cancer: a review of the literature". Eur J Cancer. 34 (7): 977–86. PMID 9849443.