Merkel cell cancer surgery

	Merkel cell cancer Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Merkel Cell Cancer from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Staging
History and Symptoms
Physical Examination
Laboratory Findings
CT
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Merkel cell cancer surgery On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Merkel cell cancer surgery All Images X-rays Echo and Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Merkel cell cancer surgery
CDC on Merkel cell cancer surgery
Merkel cell cancer surgery in the news
Blogs on Merkel cell cancer surgery
Directions to Hospitals Treating Merkel cell cancer
Risk calculators and risk factors for Merkel cell cancer surgery

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]

Overview

The predominant therapy for Merkel cell cancer is surgical resection.

The initial standard approach for patients with merkel cell cancer is wide excision.
According to:^[1]
- European Dermatology Forum (EDF)
- European Association of Dermato-Oncology (EADO)
- European Organization of Research and Treatment of Cancer (EORTC) the primary tumour should be excised a margin of at least 1 to 2 cm of healthy tissue surrounding it is recommended.
Overall survival rate in patients with merkel cell cancer increases dramatically by achieving negative margins during excision of the tumour.^[2]
Regional lymph nodes are often resection because they may contain cancer cells.

Mohs micrographic surgery is indicated when considered cosmetic outcomes especially on sensitive body parts like face.^[3]

↑ Lebbe C, Becker JC, Grob JJ, Malvehy J, Del Marmol V, Pehamberger H, Peris K, Saiag P, Middleton MR, Bastholt L, Testori A, Stratigos A, Garbe C (November 2015). "Diagnosis and treatment of Merkel Cell Carcinoma. European consensus-based interdisciplinary guideline". Eur. J. Cancer. 51 (16): 2396–403. doi:10.1016/j.ejca.2015.06.131. PMID 26257075.
↑ Tai PT, Yu E, Tonita J, Gilchrist J (October 2000). "Merkel cell carcinoma of the skin". J Cutan Med Surg. 4 (4): 186–95. doi:10.1177/120347540000400403. PMID 11231196.
↑ O'Connor WJ, Roenigk RK, Brodland DG (October 1997). "Merkel cell carcinoma. Comparison of Mohs micrographic surgery and wide excision in eighty-six patients". Dermatol Surg. 23 (10): 929–33. PMID 9357504.