Gonadoblastoma history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
Patients with gonadoblastoma present either during infancy with ambiguous genitalia or later with sexual developmental complaints. The hallmark of gonadoblastoma is gonadal developmental disorders. The majority of affected individuals are phenotypically women and may be discovered during a workup for virilization and/or primary amenorrhea. Others are phenotypically men with sex organs developmental problems such as cryptorchidism and hypospadias.Although very rarely, gonadoblastoma has been found in anatomically normal male individuals. In this individuals, it may present with a sense of discomfort or pain in testicles.
History and Symptoms
History
Patients with gonadoblastoma may have a positive history of:[1][2]
- Ambiguous genitalia
- Sexual development disorders
- Hypospadias or undescended testes
Common Symptoms
Common symptoms of gonadoblastoma include:
Less Common Symptoms
Less common symptoms of gonadoblastoma include:
- Growing mass in testicles
- Chronic pain in testis
- Low abdominal mass in phenotypically normal women