Desmoid tumor future or investigational therapies

Desmoid tumor Microchapters
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Case #1

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]

Future or Investigational therapies

• Following investigational therapies might prove fruitful in future for treatment of desmoid tumors:

Angiogenesis inhibitors

• Newer substances that may be able to prevent the growth of tumors by blocking the formation of new blood vessels that feed the tumors are being currently investigated.

Chemotherapy agents

• Researchers are also testing several chemotherapy drugs, or combination of drugs, that could prove to be most effective in treating desmoid tumors to avoid radical management via surgery.

===Mutations in the gene for beta-catenin==-

• These mutations have been found to commonly occur in desmoid tumor
• Mutation analysis may soon be used to predict the risk of recurrence and to aid in the design of individual therapies

Source

• Information on current clinical trials is posted on the Internet at www.clinicaltrials.gov
• National Organization for Rare Disorders (NORD) https://rarediseases.org/rare-diseases/desmoid-tumor/