Zollinger-Ellison syndrome historical perspective
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]
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Overview
In 1955, Zollinger and Ellison published their seminal paper on gastrinomas wherein the Zollinger-Ellison syndrome was first discussed.
Historical Perspective
- In 1955, Zollinger and Ellison announced their concept about ulcerogenic islet cell tumor which caused marked ulcer diathesis due to gastric hyperacidity.[1]
- Dr. Robert M. Zollinger and Dr. Edwin H. Ellison announced their theory at annual meeting of the American Surgical Association in Philadelphia in April 1956.[2]
- This concept raised from clinical case of two women who presented with perforated jejunal ulcers accompanied with severe ulcer diathesis.
- In 1960s, gastrin was described as a main pathogenesis of gastric hyperacidity.[3]
References
- ↑ Zollinger RM (1991). "[The history of the Zollinger-Ellison syndrome]". Ann Gastroenterol Hepatol (Paris). 27 (5): 223–6. PMID 1746876.
- ↑ ZOLLINGER RM, ELLISON EH (1955). "Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas". Ann Surg. 142 (4): 709–23, discussion, 724–8. PMC 1465210. PMID 13259432.
- ↑ Hou W, Schubert ML (2006). "Gastric secretion". Curr Opin Gastroenterol. 22 (6): 593–8. doi:10.1097/01.mog.0000245538.43142.87. PMID 17053435.