Carcinoma of the penis historical perspective

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Overview

In 1965, the first published HPV study characterized its DNA
Prior to 1965, papillomavirus studies focused on rabbit papillomavirus and its association to cancer
During the 1970’s, more than one type of HPV was recognized
In 1982, several studies associating HPV type 6 with genital warts, but neither cervical nor penile cancer, were published
The theory that penile and cervical cancer may have a common etiology was proposed as early as 35 years ago
Initial studies supported a causal relationship between male sexual behaviors and the incidence of cervical carcinoma before the role of HPV was even recognized