Vulvar cancer differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]

Overview

Vulvar cancer must be differentiated from other neoplastic vulvar lesions, non neoplastic vulvar lesions, and infectious disease lesions of vulva.

Differentiating vulvar cancer from other Diseases

• Vulvar cancer must be differentiated from other neoplastic vulvar lesions such as:

• Paget disease of the vulva
• Vulvar intraepithelial neoplasm (VIN)

• Vulvar cancer must be differentiated from other non neoplastic vulvar lesions such as:

• Lichen sclerosus
• Squamous cell hyperplasia
• Vulvar vestibulitis

• Vulvar cancer must be differentiated from infectious disease lesions of vulva such as:

• Herpes genitalis
• Human papillomavirus
• Syphilis
• Chancroid
• Granuloma inguinale
• Lymphogranuloma venereum