Loefflers syndrome differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Loeffler syndrome must be differentiated from other diseases that cause pulmonary eosinophilia, such as Churg-Strauss, drug and toxin-induced eosinophilic lung diseases, other helminthic and fungal infection related eosinophilic lung diseases, and nonhelminthic infections such as Coccidioidomycosis, and Mycobacterium tuberculosis, .

Differentiating Loeffler syndrome from other pulmonary eosinophilia syndromes on the basis of etiology.

Diseases		Clinical manifestations						Para-clinical findings							Gold standard	Additional findings
		Symptoms			Physical examination
								Lab Findings			Imaging			Histopathology
		Symptom 1	Symptom 2	Symptom 3	Physical exam 1	Physical exam 2	Physical exam 3	Lab 1	Lab 2	Lab 3	Imaging 1	Imaging 2	Imaging 3
Helminthic and fungal infection-related eosinophilic lung diseases	Transpulmonary passage of larvae (Loffler's syndrome)
	Tropical pulmonary eosinophilia
	Allergic bronchopulmonary aspergillosis
	Heavy hematogenous seeding with helminths
	Pulmonary parenchymal invasion
Nonhelminthic infections	Coccidioidomycosis
	Mycobacterium tuberculosis
	Eosinophilic granulomatosis with polyangiitis (Churg-Strauss)
	Drug- and toxin-induced eosinophilic lung diseases
	Acute eosinophilic pneumonia
	Chronic eosinophilic pneumonia
Diseases		Symptom 1	Symptom 2	Symptom 3	Physical exam 1	Physical exam 2	Physical exam 3	Lab 1	Lab 2	Lab 3	Imaging 1	Imaging 2	Imaging 3	Histopathology	Gold standard	Additional findings
	Differential Diagnosis 7
	Differential Diagnosis 7
	Differential Diagnosis 7
	Differential Diagnosis 7