Ganglioneuroma differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Ganglioglioma must be differentiated from neuroblastoma, ganglioneuroblastoma, spinal schwannoma, spinal neurofibroma, adrenal adenoma, adrenal carcinoma, and pheochromocytoma.^[1]^[2]

Ganglioneuroma must be differentiated from the following conditions:^[1]^[2]


Differential Diagnosis	Differentiating Features

Neuroblastoma Ganglioneuroblastoma	Metastases indicates neuroblastoma or ganglioneuroblastoma Tumor calcification in neuroblastoma is more often amorphous and of a rough pattern Cannot be differentiated from ganglioneuroma based on imaging characteristics
Spinal schwannoma and neurofibroma	Centred on neural foramen Seen in middle-aged adults
Adrenal adenoma Adrenal carcinoma Pheochromocytoma	Masses in the adrenal gland

↑ ^1.0 ^1.1 D.Dx of ganglioneuroma. Dr Bruno Di Muzio and Dr Yuranga Weerakkody et al. Radiopaedia 2015. http://radiopaedia.org/articles/ganglioneuroma
↑ ^2.0 ^2.1 Adam, O; Boia, ES (2007). "ganglioneuroma" (PDF). jurnalul pediatrului. 10 (39–40). Retrieved 10 September 2015.