Palmar plantar erythrodysesthesia primary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

· A number of measures have been suggested to prevent, delay onset and/or decrease the severity of PPE: · General measures include^4,7,99,102: · Avoiding excessive manual work and walking, to prevent excessive pressure or friction to the skin · Wound care to prevent infection · Limb elevation to reduce edema · Cold compresses · Avoiding extremes of temperature⁸ · Analgesics · Creams and emollients