Lipoid pneumonia historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]
Overview
In 1925,G. F. LAUGHLEN, M.D. was the first physician to describe lipoid pneumonia. he first interacted to the disease by routine autopsy at the Toronto, Ontorio hospital for sick children. he described grayish red nodules at the autopsy with three types of exudates, found out mononuclear cells which were unexpected in the exudates. in 1949 McDonald et al described endogenous lipoid pneumonia for the first time. he observed so called "obstructive pneumonia" in patients with lung neoplasms.
Historical Perspective
Discovery
- In 1925,G. F. LAUGHLEN, M.D. was the first physician to describe exogenus lipoid pneumonia.[1]
- He first interacted to the disease by routine autopsy at the Toronto, Ontorio hospital for sick children.
- He described grayish red nodules at the autopsy with three types of exudates, found out mononuclear cells which were unexpected in the exudates.
- All of his 4 observed cases underwent laxative and nasal drop therapy regimen.
- In 1949 McDonald et al described endogenous lipoid pneumonia for the first time.[2]
- He observed so called "obstructive pneumonia" in patients with lung neoplasms.
References
- ↑ Laughlen GF (July 1925). "Studies on Pneumonia Following Naso-Pharyngeal Injections of Oil". The American Journal of Pathology. 1 (4): 407–414.1. PMC 1931653. PMID 19969662.
- ↑ McDONALD JR, HARRINGTON SW, CLAGETT OT (1949). "Obstructive pneumonitis of neoplastic origin; an interpretation of one form of so-called atelectasis and its correlation according to presence of absence of sputum". J Thorac Surg. 18 (1): 97–112, disc., 122. PMID 18110247.