Patent foramen ovale history and symptoms

Patent Foramen Ovale Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [3]

Overview

The vast majority of patients with a patent foramen ovale do not have symptoms. Patients with right-to-left shunting can have cyanosis. These cyanosis episode might get exacerbated in case of increased pressure in pulmonary vasculature like breath holding, crying, or the valsalva maneuver.

History and Symptoms

• The majority of patients with patent foramen ovale are asymptomatic. Due to the pathway a patent foramen ovale creates, chemicals or thrombus can travel through resulting in clinical manifestations such as stroke, migraine headache, high altitude pulmonary edema, decompression sickness, and platypnea-orthodeoxia syndrome.