Patent foramen ovale diagnostic study of choice
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ifeoma Odukwe, M.D. [2]
Overview
- The diagnostic study of choice for patent foramen ovale is contrast-enhanced transesophageal echocardiography (c-TEE).
Diagnostic Study of Choice
Study of choice
The diagnostic study of choice for patent foramen ovale is contrast-enhanced transesophageal echocardiography (c-TEE).[1]
The comparison of various diagnostic studies for patent foramen ovale
| Test | Sensitivity | Specificity |
|---|---|---|
| Transesophageal echocardiography | 89% | 100% |
| Transthoracic echocardiography | 46% | 99% |
| Transcranial doppler | 96% | 93% |
Diagnostic results
The following finding on performing contrast-enhanced transesophageal echocardiography is confirmatory for patent foramen ovale:[2][3][4]
- Presence of bubbles across the inter-atrial septum into the left atrium: A diagnosis is made with the appearance of at least three micro-bubbles within three cardiac cycles after the complete opacification of the right atrium.
References
- ↑ Pearson AC, Labovitz AJ, Tatineni S, Gomez CR (1991). "Superiority of transesophageal echocardiography in detecting cardiac source of embolism in patients with cerebral ischemia of uncertain etiology". J Am Coll Cardiol. 17 (1): 66–72. doi:10.1016/0735-1097(91)90705-e. PMID 1987242.
- ↑ Pinto FJ (2005). "When and how to diagnose patent foramen ovale". Heart. 91 (4): 438–40. doi:10.1136/hrt.2004.052233. PMC 1768819. PMID 15772190.
- ↑ Mas, Jean-Louis; Arquizan, Caroline; Lamy, Catherine; Zuber, Mathieu; Cabanes, Laure; Derumeaux, Geneviève; Coste, Joël (2001). "Recurrent Cerebrovascular Events Associated with Patent Foramen Ovale, Atrial Septal Aneurysm, or Both". New England Journal of Medicine. 345 (24): 1740–1746. doi:10.1056/NEJMoa011503. ISSN 0028-4793.
- ↑ Yuan, Kristy; Kasner, Scott Eric (2018). "Patent foramen ovale and cryptogenic stroke: diagnosis and updates in secondary stroke prevention". Stroke and Vascular Neurology. 3 (2): 84–91. doi:10.1136/svn-2018-000173. ISSN 2059-8688.