Cluster headache causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sabeeh Islam, MBBS[2]
Overview
Cluster headaches are generally associated with underlying neurologic conditions and structural abnormalities of brain and the pituitary gland. Common causes include; Chronic paroxysmal hemicrania (CPH), Subarachnoid hemorrhage, Trigeminal Neuralgia, Cyclical migraine, Hemicrania continua, Intermittent hydrocephalus, Sleep apnea, Acute optic neuritis, Acute glaucoma, Acute hypertension, Cerebral venous thrombosis, and Interior carotid artery dissection.
Causes
Cluster headaches are generally associated with underlying neurologic conditions and structural abnormalities of brain and the pituitary gland. Common causes include; Chronic paroxysmal hemicrania (CPH), Subarachnoid hemorrhage, Trigeminal Neuralgia, Cyclical migraine, Hemicrania continua, Intermittent hydrocephalus, Sleep apnea, Acute optic neuritis, Acute glaucoma, Acute hypertension, Cerebral venous thrombosis, and Interior carotid artery dissection.
| Cardiovascular | Acute hypertension, Cerebral venous thrombosis, Interior carotid artery dissection |
| Chemical / poisoning | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | Sinusitis |
| Endocrine | Pheochromocytoma |
| Environmental | Smoking or secondary exposure to tobacco smoke |
| Gastroenterologic | No underlying causes |
| Genetic | Monozygotic twins |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | Herpes Zoster |
| Musculoskeletal / Ortho | No underlying causes |
| Neurologic | Chronic paroxysmal hemicrania (CPH), Subarachnoid hemorrhage, Trigeminal Neuralgia, Cyclical migraine, Hemicrania continua, Intermittent hydrocephalus, Sleep apnea |
| Nutritional / Metabolic | No underlying causes |
| Obstetrics and Gynecology | Preeclampsia |
| Oncologic | Intracranial neoplasm |
| Opthalmologic | Acute optic neuritis, Acute glaucoma |
| Overdose / Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal / Electrolyte | No underlying causes |
| Rheum / Immune / Allergy | Temporal Arteritis, Allergen exposure, Connective tissue disorder (e.g., systemic lupus erythematosus SLE) |
| Trauma | Cranial trauma |
| Miscellaneous | No underlying causes |
References
Russell MB, Andersson PG, Thomsen LL (March 1995). "Familial occurrence of cluster headache". J. Neurol. Neurosurg. Psychiatry. 58 (3): 341–3. doi:10.1136/jnnp.58.3.341. PMC 1073373. PMID 7897418.
El Amrani M, Ducros A, Boulan P, Aidi S, Crassard I, Visy JM, Tournier-Lasserve E, Bousser MG (2002). "Familial cluster headache: a series of 186 index patients". Headache. 42 (10): 974–7. doi:10.1046/j.1526-4610.2002.02226.x. PMID 12453028.
Leone M, Russell MB, Rigamonti A, Attanasio A, Grazzi L, D'Amico D, Usai S, Bussone G (May 2001). "Increased familial risk of cluster headache". Neurology. 56 (9): 1233–6. doi:10.1212/wnl.56.9.1233. PMID 11342697.