Asperger syndrome differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Differentiating Asperger Syndrome from other Disorders

Conditions that must be considered in a differential diagnosis include

• Other ASDs
• Schizophrenia spectrum
• ADHD
• Obsessive compulsive disorder
• Depression
• Semantic pragmatic disorder
• Nonverbal learning disorder
• Tourette syndrome
• Stereotypic movement disorder
• Bipolar disorder.

Asperger Syndrome Differential Diagnosis

Asperger Syndrome Differential Diagnosis (Modified Table from The Investigation and Differential Diagnosis of Asperger Syndrome in Adults )
	Asperger Syndrome	Schizoid Personality Disorder	Schizotypal Personality Disorder	Avoidant Personality Disorder	Social Phobia	Obsessive Personality Disorder	Obsessive-compulsive disorder (OCD)	Attention deficit–hyperactivity disorder (ADHD)
Abnormal social interaction	+	+	+	+	+	+	+	+
Abnormal verbal communication	+	+	+	-	-	-	-	-
Abnormal facial expression/gestures/prosody	+	+	+	+	+/-	-	-	+/-
Abnormal eye contact	+	+	+/-	+	+/-	-	-	+/-
Abnormal theory of mind	+	+/-	+/-	+/-	+/-	+/-	-	+/-
Abnormal empathy	+	+/-	+/-	-	-	+/-	-	+/-
Abnormal interests/rituals/compulsions	+	+/-	+/-	-	-	+	+	-
Abnormal attention	+/-	-	-	-	-	-	-	+
Abnormal psychomotor function	+	-	+/-	-	-	-	-	+/-
Abnormal self-injurious behavior	+/-	+/-	+/-	-	-	-	-	+/-
Abnormal psychotic manifestations	+/-	-	+/-	-	-	-	-	-
Abnormal social interaction in childhood	+	+/-	+/-	+/-	-	-	-	+
Abnormal biographical stress factors	-	+	+/-	+	+/-	+	+/-	+/-

References

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