COVID-19 other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]
Overview
Research laboratories have used isolation methods, electron microscopy, serology and PCR-based assays to diagnose coronavirus infections for surveillance studies.
Other Diagnostic Studies
Specific laboratory tests may include:
- Virus isolation in cell culture.
- Polymerase chain reaction (PCR) assays that are more practical and available commercially.
- Serological testing for antibodies to human coronaviruses.
Nose and throat swabs are the best specimens for detecting common human coronaviruses. Serological testing requires the collection of blood specimens.[1]
Gallery
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SEM reveals the “rosette-like” appearance of the matured coronavirus particles. From Public Health Image Library (PHIL). [2]
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TEM revealed the presence of a number of infectious bronchitis virus (IBV) virions. From Public Health Image Library (PHIL). [2]
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Scanning electron micrograph reveals the prolific exportation of virus particles at the pseudopodial and cell surfaces. From Public Health Image Library (PHIL). [2]
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Scanning electron micrograph reveals the prolific exportation of virus particles at the pseudopodial and cell surfaces. From Public Health Image Library (PHIL). [2]
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TEM from a tissue culture isolate, revealing numbers of severe acute respiratory virus (SARS) virions. From Public Health Image Library (PHIL). [2]
References
- ↑ Tang YW, Schmitz JE, Persing DH, Stratton CW (2020). "Laboratory Diagnosis of COVID-19: Current Issues and Challenges". J Clin Microbiol. 58 (6). doi:10.1128/JCM.00512-20. PMC 7269383 Check
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value (help). PMID 32245835 Check|pmid=
value (help). - ↑ 2.0 2.1 2.2 2.3 2.4 "Public Health Image Library (PHIL)".