Bartter syndrome natural history, complications and prognosis
|
Bartter syndrome Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Bartter syndrome natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Bartter syndrome natural history, complications and prognosis |
|
FDA on Bartter syndrome natural history, complications and prognosis |
|
CDC on Bartter syndrome natural history, complications and prognosis |
|
Bartter syndrome natural history, complications and prognosis in the news |
|
Blogs on Bartter syndrome natural history, complications and prognosis |
|
Risk calculators and risk factors for Bartter syndrome natural history, complications and prognosis |
Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History
Complications
Kidney failure is a possible complication.
- Bartter syndrome type I and type II are salt-wasting renal tubular disorders that are clinically characterized by polyhydramnios leading to premature delivery, marked polyuria, and a tendency towards nephrocalcinosis.[1]16773399
- Gallstones might represent a new complication of antenatal Bartter syndrome.[2]
Prognosis
The limited prognostic information available suggests that early diagnosis and appropriate treatment of infants and young children with classic Bartter Syndrome (type 3) may improve growth and perhaps neuro-intellectual development. On the other hand, sustained hypokalemia and hyperreninemia can cause progressive tubulointerstitial nephritis, resulting in end-stage renal disease (Kidney failure). With the early treatment of the electrolyte imbalances, the prognosis for patients with Classic Bartter Syndrome is good.
- Patients with Bartter syndrome type I and II tend to present a satisfactory prognosis after a median follow-up of more than 10 years.[2]
References
- ↑ Seyberth HW (2008). "An improved terminology and classification of Bartter-like syndromes". Nat Clin Pract Nephrol. 4 (10): 560–7. doi:10.1038/ncpneph0912. PMID 18695706.
- ↑ 2.0 2.1 Puricelli E, Bettinelli A, Borsa N, Sironi F, Mattiello C, Tammaro F; et al. (2010). "Long-term follow-up of patients with Bartter syndrome type I and II". Nephrol Dial Transplant. 25 (9): 2976–81. doi:10.1093/ndt/gfq119. PMID 20219833.