Renal agenesis classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Classification
Bilateral renal agenesis
Bilateral renal agenesis is uncommon and is a serious condition. See Potter syndrome.
Bilateral Renal Agenesis is the absence of both kidneys at birth. It is a genetic disorder characterized by a failure of the kidneys to develop in a fetus. This absence of kidneys causes a deficiency of amniotic fluid (Oligohydramnios) in a pregnant woman. Normally, the amniotic fluid acts as a cushion for the developing fetus. When there is an insufficient amount of this fluid, compression of the fetus may occur resulting in further malformations of the baby.
This disorder is more common in infants born of a parent who has a kidney malformation, particularly the absence of one kidney (unilateral renal agenesis). Studies have proven that unilateral renal agenesis and bilateral renal agenesis are genetically related. 1 in 3 infants with this congenital defect are still born. Most infants that are born alive do not live beyond four hours.
Unilateral renal agenesis
This is much more common, but is not usually of any major concern, as long as the other kidney is healthy. The odds of a person being born with this condition are roughly 1 in 5000. Adults with unilateral renal agenesis have considerably higher chances of hypertension and high blood pressure. Most contact sports would be advised against.
Overview
Classification
Renal agenesis may be unilateral or bilateral:[1]
- Unilateral renal agenesis(URA)
- Bilateral renal agenesis (BRA)
References
- ↑ 1.0 1.1 Dias T, Sairam S, Kumarasiri S (2014). "Ultrasound diagnosis of fetal renal abnormalities". Best Pract Res Clin Obstet Gynaecol. 28 (3): 403–15. doi:10.1016/j.bpobgyn.2014.01.009. PMID 24524801.
- ↑ Robson WL, Leung AK, Rogers RC (1995). "Unilateral renal agenesis". Adv Pediatr. 42: 575–92. PMID 8540439.
- ↑ Woolf AS, Hillman KA (2007). "Unilateral renal agenesis and the congenital solitary functioning kidney: developmental, genetic and clinical perspectives". BJU Int. 99 (1): 17–21. doi:10.1111/j.1464-410X.2006.06504.x. PMID 16956352.
- ↑ Cho JY, Moon MH, Lee YH, Kim KW, Kim SH (2009). "Measurement of compensatory hyperplasia of the contralateral kidney: usefulness for differential diagnosis of fetal unilateral empty renal fossa". Ultrasound Obstet Gynecol. 34 (5): 515–20. doi:10.1002/uog.7336. PMID 19852048.
- ↑ Huber C, Shazly SA, Blumenfeld YJ, Jelin E, Ruano R (2019). "Update on the Prenatal Diagnosis and Outcomes of Fetal Bilateral Renal Agenesis". Obstet Gynecol Surv. 74 (5): 298–302. doi:10.1097/OGX.0000000000000670. PMID 31098643.