Urticaria natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History, Complications, and Prognosis
Natural History
- Remission rate of chronic urticaria has been estimated from 10% to 60% within the first 5–10 years of disease diagnosis. Moreover, data showed higher remission rate in patients younger than 20 years old. [1]
- Most cases with cholinergic urticaria have mild symptoms and 80% of patinets don't seek medical attention.
- The following table contains mean duration of some subtypes of urticaria.[2]
Cold contact urticaria | 4.2 years |
Delayed‐pressure urticaria | 6–9 years |
Dermographic urticaria | 6.5 years |
Complications
- Common complications of [disease name] include:
- [Complication 1]
- [Complication 2]
- Pressure urticaria might turn into a debilitating disease in some occupations.[2]
Prognosis
- Most patients improve over time, even stubborn cases.[3]
- Prognosis and treatment response is better in patients younger than 19 years old, compared to older adults.[3][4]
- The following are some factors related to worse urticaria prognosis:[5][6][7]
- Female gender
- Prolonged period of disease at the first visit
- Concurrent presentation of angioedema
- Physical urticaria
- Non-steroidal anti-inflammatory drug
References
- ↑ Tanaka T, Hiragun M, Hide M, Hiragun T (2017). "Analysis of primary treatment and prognosis of spontaneous urticaria". Allergol Int. 66 (3): 458–462. doi:10.1016/j.alit.2016.12.007. PMID 28094108.
- ↑ 2.0 2.1 Zuberbier T (2003). "Urticaria". Allergy. 58 (12): 1224–34. doi:10.1046/j.1398-9995.2003.00327.x. PMID 14616095.
- ↑ 3.0 3.1 Hiragun M, Hiragun T, Mihara S, Akita T, Tanaka J, Hide M (2013). "Prognosis of chronic spontaneous urticaria in 117 patients not controlled by a standard dose of antihistamine". Allergy. 68 (2): 229–35. doi:10.1111/all.12078. PMID 23205732.
- ↑ Gregoriou S, Rigopoulos D, Katsambas A, Katsarou A, Papaioannou D, Gkouvi A; et al. (2009). "Etiologic aspects and prognostic factors of patients with chronic urticaria: nonrandomized, prospective, descriptive study". J Cutan Med Surg. 13 (4): 198–203. doi:10.2310/7750.2008.08035. PMID 19706227.
- ↑ Puxeddu I, Petrelli F, Angelotti F, Croia C, Migliorini P (2019). "Biomarkers In Chronic Spontaneous Urticaria: Current Targets And Clinical Implications". J Asthma Allergy. 12: 285–295. doi:10.2147/JAA.S184986. PMC 6759208 Check
|pmc=
value (help). PMID 31571935. - ↑ Toubi E, Kessel A, Avshovich N, Bamberger E, Sabo E, Nusem D; et al. (2004). "Clinical and laboratory parameters in predicting chronic urticaria duration: a prospective study of 139 patients". Allergy. 59 (8): 869–73. doi:10.1111/j.1398-9995.2004.00473.x. PMID 15230821.
- ↑ Folci M, Heffler E, Canonica GW, Furlan R, Brunetta E (2018). "Cutting Edge: Biomarkers for Chronic Spontaneous Urticaria". J Immunol Res. 2018: 5615109. doi:10.1155/2018/5615109. PMC 6280255. PMID 30584542.