Lymphadenopathy classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2], Raviteja Guddeti, M.B.B.S. [3]
Overview
Lymphadenopathy may be classified according to distribution into 2 groups localized lymphadenopathy and generalized lymphadenopathy.
Classification
Depending upon the involvement of the lymph nodes, lymphadenopathy is classified into 2 groups:[1]
- Localized lymphadenopathy: due to localized spot of infection e.g. an infected spot on the scalp will cause lymph nodes in the neck on that same side to swell up
- Generalized lymphadenopathy: due to generalized infection all over the body e.g. influenza
- Persistent generalized lymphadenopathy (PGL): persisting for a long time, possibly without an apparent cause
- Dermatopathic lymphadenopathy: lymphadenopathy associated with skin disease. Tangier disease (ABCA1 deficiency) may also cause this.