Lymphadenopathy history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2], Raviteja Guddeti, M.B.B.S. [3]
Overview
The hallmark of lymphadenopathy is swollen lymph node. A positive history of a lump in the neck, red, tender skin over lymph node, and swollen, tender, or hard lymph nodes is suggestive of lymphadenopathy. The most common symptoms of lymphadenopathy include a lump in neck or affected part and constitutional symptoms like fatigue, fever, malaise, flu- like illness, nausea and vomiting, night sweats, weight loss, and cachexia.
History and Symptoms
History
A directed history should be obtained to ascertain:[1]
- Constitutional symptoms like night sweats, fever, weight loss suggesting tuberculosis, Hodgkin's lymphoma, other malignancy
- Associated signs and symptoms for suggesting infections or malignancy
- Use of drugs causing lymphadenopathy
- Travel to endemic areas
- High-risk behavior- high-risk sexual behavior, I.V drug abuse
Patients with lymphadenopathy may have a positive history of:
- Lump in the neck (e.g. in tumors, sarcoidosis).
- Red, tender skin over lymph node.
- Swollen, tender, or hard lymph nodes.
Common Symptoms
Common symptoms of lymphadenopathy include:
- Lump in the neck
- Red, tender skin over lymph node.
- Swollen, tender, or hard lymph nodes.
- Constituitional symptoms like:[2]
- Fatigue
- Fever
- Malaise
- Flu- like illness
- Nausea and vomiting
- Night sweats
- Weight loss and
- Cachexia