Lymphadenopathy CT scan

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]

Overview

A Chest CT scan may be helpful in the diagnosis of hilar adenopathy. Findings on CT scan suggestive of/diagnostic of tuberculosis, sarcoidosis, lymphoma, and other malignancies. Abdominal and pelvic CT scan in combination with chest CT scan can be revealed in cases of supraclavicular adenopathy and the diagnosis of secondary neoplasm.

CT scan

• On CT, characteristic findings of lymphadenopathy, include:

• Most nodes: 10 mm in short-axis
• Sub-mental and sub-mandibular: 15 mm
• Retropharyngeal: 8 mm
• Loss of fatty hilum
• Focal necrosis
• Cystic necrotic nodes
• Long-to-short axis ratio (>2cm - usually benign)

• The upper limit in size of a normal node varies with location.

[Location] CT scan may be helpful in the diagnosis of [disease name]. Findings on CT scan suggestive of/diagnostic of [disease name] include:

• [Finding 1]

PET/CT

• On PET/CT, lymphadenopathy can be further assessed via quantitation of FDG uptake, which is a surrogate of metabolic activity. Infectious, inflammatory, and neoplastic processes will show high FDG avidity on PET/CT. PET/CT is particularly useful for assessing response of lymph nodes to systemic chemotherapy.