Anaphylaxis natural history, complications and prognosis

Anaphylaxis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Dushka Riaz, MD

Overview

If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

OR

Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].

OR

Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.

Natural History, Complications, and Prognosis

Natural History

• The symptoms of anaphylaxis usually develop within seconds with rapid evolution. It usually carries an unpredictable course and can resolve as quickly as it began. If left untreated, anaphylaxis can progress to respiratory or cardiovascular compromise.

Complications

Possible complications include:

• Airway blockage
• Cardiac arrest (no effective heartbeat)
• Respiratory arrest (no breathing)
• Shock

Prognosis

Anaphylaxis is a severe disorder that can be life-threatening without prompt treatment. However, symptoms usually get better with the right therapy, so it is important to act right away. Depending on the availability of epinephrine treatment, the prognosis may vary.