Autoimmune lymphoproliferative syndrome physical examination

Autoimmune lymphoproliferative syndrome Microchapters
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Editor-In-Chief: David Teachey, MD [1]

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Physical Examination

Skin

• Pallor
• Rash
• Petechiae

Head

• Lymphadenopathy: >90% of patients present with chronic non-malignant lymphadenopathy. It can be mild to severe, affecting multiple nodal groups. Most commonly presents with massive non-painful hard cervical lymphadenopathy

Abdomen

• Splenomegaly: >80% of patients present with clinically identifiable splenomegaly. It can be massive.
• Hepatomegaly: 30-40% of patients have enlarged livers.