Alcoholic hepatitis surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2] M. Khurram Afzal, MD [3]
Overview
Liver transplant is considered in case of cirrhosis. Orthotopic liver transplant is the definitive surgical treatment for hepatic failure associated with Alcoholic Hepatitis. Prior to liver transplant, 6 months of abstinence is required.
Surgery
Liver transplant
- If cirrhosis develops, there is a need to manage the complications of cirrhosis. It may need a liver transplant.[1]
- Orthotopic liver transplant (OLT) is the definitive surgical treatment for hepatic failure associated with Alcoholic hepatitis.[2]
- Due to the nature of the disease being considered as self induced and the possibility of recidivism most patients are not considered for OLT.[3][4]
- These patients should be evaluated for likelihood of long term abstinence from alcohol, a six month period of abstinence before transplant may even allow clinical improvement.[5]
References
- ↑ Biselli M, Gramenzi A, Del Gaudio M, Ravaioli M, Vitale G, Gitto S, Grazi GL, Pinna AD, Andreone P, Bernardi M (2010). "Long term follow-up and outcome of liver transplantation for alcoholic liver disease: a single center case-control study". J. Clin. Gastroenterol. 44 (1): 52–7. doi:10.1097/MCG.0b013e3181a390a8. PMID 19581813.
- ↑ Arteel G, Marsano L, Mendez C, Bentley F, McClain CJ (2003). "Advances in alcoholic liver disease". Best Pract Res Clin Gastroenterol. 17 (4): 625–47. PMID 12828959.
- ↑ O'Grady JG (2006). "Liver transplantation alcohol related liver disease: (deliberately) stirring a hornet's nest!". Gut. 55 (11): 1529–31. doi:10.1136/gut.2005.090506. PMC 1860102. PMID 17047102.
- ↑ Mackie J, Groves K, Hoyle A, Garcia C, Garcia R, Gunson B, Neuberger J (2001). "Orthotopic liver transplantation for alcoholic liver disease: a retrospective analysis of survival, recidivism, and risk factors predisposing to recidivism". Liver Transpl. 7 (5): 418–27. doi:10.1053/jlts.2001.23789. PMID 11349262.
- ↑ Lucey MR, Brown KA, Everson GT, Fung JJ, Gish R, Keeffe EB, Kneteman NM, Lake JR, Martin P, McDiarmid SV, Rakela J, Shiffman ML, So SK, Wiesner RH (1997). "Minimal criteria for placement of adults on the liver transplant waiting list: a report of a national conference organized by the American Society of Transplant Physicians and the American Association for the Study of Liver Diseases". Liver Transpl Surg. 3 (6): 628–37. PMID 9404965.