Bornholm disease causes
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Arooj Naz
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Overview
Bornholm disease usually is caused by one of the group B coxsackie viruses and is less often caused by a group A coxsackie virus or an echovirus.
Causes
Bornholm disease is often due to either the Coxsackie virus or echovirus. The most prevalent strains include:
- Coxsackievirus B (CBV) types B3 and B4
- Coxsackievirus A (CAV) types 4, 6, 9 and 10
- Echovirus types 1, 6, 8, 9 and 19
Generally, Coxsackievirus B virus is more prevalent in regards to respiratory complaints compared to Coxsackievirus A strains. Apart from respiratory symptoms, the Coxsackievirus B virus has also presented with cases of aseptic meningitis, pericarditis, and orchitis. [1] The clinical spectrum varies depending on age groups for the Coxsackievirus A and B strains of the virus. Although severe progression of the disease is rare, it has been associated in particular with the Coxsackievirus B3 virus.[2]
References
- ↑ Lal A, Akhtar J, Isaac S, Mishra AK, Khan MS, Noreldin M | display-authors=etal (2018) Unusual cause of chest pain, Bornholm disease, a forgotten entity; case report and review of literature. Respir Med Case Rep 25 ():270-273. DOI:10.1016/j.rmcr.2018.10.005 PMID: 30364740
- ↑ Lee CJ, Huang YC, Yang S, Tsao KC, Chen CJ, Hsieh YC; et al. (2014). "Clinical features of coxsackievirus A4, B3 and B4 infections in children". PLoS One. 9 (2): e87391. doi:10.1371/journal.pone.0087391. PMC 3913601. PMID 24504149.