Cavernous angioma historical perspective
Editor-in-Chief: =Edzel Lorraine Co, DMD, MD=
Current Position
Associate Editor-in-Chief, Beth Israel Deaconess Medical Center by Harvard Medical School, Boston, Massachusetts, USA, WikiDoc Scholar, January 2022 - present
Professional Background
Dr. Co is a licensed physician and dentist in the Philippines. She is an optimistic and hardworking person committed to providing high-quality health care services in the fields of medicine and dentistry. Her knowledge and skills acquired from her training in medical and dental school led her to become a compassionate, caring, and competent clinician who treats patients holistically.
Education
- Doctor of Medicine, University of Santo Tomas Faculty of Medicine and Surgery, Manila, Philippines, 2013 - 2017
- Doctor of Dental Medicine, University of the Philippines Manila, Manila, Philippines, 2006 - 2012
- Philippine Science High School Main Campus, Manila, Philippines, 2003-2006
Pages Authored/Co-authored/Collaborated
- 2-(4-chlorphenoxy)-ethanol
- AbobotulinumtoxinA
- Abrocitinib
- Adams-Oliver syndrome
- Adipiodone
- Ado-Trastuzumab Emtansine
- Atrioventricular Block
- Capivasertib
- Cardiomyopathy
- Cavernous Angioma
- Cipaglucosidase alfa-atga
- Congestive Heart Failure
- Daridorexant
- Eczema
- Efbemalenograstim alfa-vuxw
- Elranatamab-bcmm
- Faricimab-svoa
- Fruquintinib
- Ganaxolone
- Gangrene
- Iptacopan
- Long COVID
- Lutetium (177Lu) vipivotide tetraxetan
- Mavacamten
- Mitapivat
- Momelotinib
- Motixafortide
- Nivolumab and relatlimab-rmbw
- Oclacitinib
- Omacetaxine mepesuccinate
- Orbifloxacin
- Oteseconazole
- Pacritinib
- Palovarotene
- Pozelimab-bbfg
- Repotrectinib
- Sudden Cardiac Death
- Sutimlimab-jome
- Taurolidine, heparin
- Tebentafusp-tebn
- Toripalimab-tpzi
- Vutrisiran
Publications
Peer Reviewed Journal Articles/Abstracts
- Co, E.L., Hameed, M., Sebastian, S.A., Garg, T., Sudan, S., Bheemisetty, N., & Mohan, B.. (2023, Aug). Narrative Review of Probiotic Use on the Recovery of Postoperative Patients with Esophageal Cancer. Current Nutrition Reports, N/A(N/A), N/A. Cited in PubMed; PMID: 37605086. Pub Status: Published. Article URL: https://doi.org/10.1007/s13668-023-00490-z
- Co, E.L., Sebastian, S.A., Maskey, U., Mehendale, M., Chowdhury, S., & Rodriguez, I.. (2022, Dec). Hybrid Closed-Loop Therapy as Management for Type 1 Diabetes Mellitus in Pregnant Patients. International Journal of Academic Medicine, 8(4), 287. Pub Status: Published. Article URL: https://journals.lww.com/ijam/Fulltext/2022/08040/Conference_proceedings__Fourth_annual_women_in.7.aspx
- Agolli, A., Ishak, A., Viswanathan, M., Co, E.L., Shivakumar, J., Agolli, O.. (2023, Apr). Epstein-Barr Viral Infection and the Risk for Breast Cancer: A Systematic Review. International Journal of Hematology Oncology and Stem Cell Research, 17(2), 114-125.Cited in PubMed; PMID: 37637768.Pub Status: Published. Article URL: https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1843
- Agolli, A., Ishak, A., Viswanathan, M., Co, E.L., Shivakumar, J., & Agolli, O.. (2023, Jan). The Oncogenic Role of Epstein-Barr Virus Infection in the Risk of Breast Cancer. Annals of Family Medicine, 21(Supplement 1), 4249.Pub Status: Published. Article URL: https://www.annfammed.org/content/21/Supplement_1/4249
- Hameed, M., Prasad, S., Jain, E., Dogrul, B.N., Al-Oleimat, A., Pokhrel, B., Chowdhury, S., Co, E.L., Mitra, S., Quinonez, J., Ruxmohan, S., & Stein,J.. (2023, Apr). Medical Cannabis for Chronic Nonmalignant Pain Management. Current Pain and Headache Reports, 27(4), 57-63. Cited in PubMed; PMID: 36897501.Pub Status: Published. Article URL: https://link.springer.com/article/10.1007/s11916-023-01101-w
- Nagy, H., Hameed, M., Khan, F., Co, E.L., & Rauf, U.. (2023, Jan). COVID-19 ramifications: a scientific approach to bridge the existing gap between COVID vaccines hesitancy and effectiveness. Avicenna Journal of Medicine, 13(1), 15-22.Cited in PubMed; PMID: 36969353.Pub Status: Published.Article URL: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0042-1760338
- Prasad, S., Shahid, A., Co, E.L., Govinda, K., Huzaifa, A.C., Rocha, I.C.N., Bardhan, M.,& Hasan, M.M.. (2022, Jul). Vaccine apartheid: the separation of the world’s poorest and most vulnerable and the birth of Omicron.. Therapeutic Advances in Vaccines and Immunotherapy, 10(25151355221107975), 1-5. Cited in PubMed; PMID: 35832726. Pub Status: Published. Article URL: https://doi.org/10.1177/25151355221107975
- Rehman, S., Salehi, M., Co, E.L., Rehman, B., & Salehi, M.. (2023, Aug). Gallbladder Angiodysplasia: A Literature Review. IJS Global Health. Pub Status: Published. Article URL: https://journals.lww.com/ijsgh/fulltext/2023/09010/gallbladder_angiodysplasia__a_literature_review.49.aspx
- Sarangi, A., Amor, W., Co, E.L., Javed, S. & Usmani, S.. (2022, Jan). Social media reinvented: can social media help tackle the post-pandemic mental health onslaught?. Cureus, 14(1), e21070. Cited in PubMed; PMID: 35155028. Pub Status: Published. Article URL: https://www.cureus.com/articles/80369-social-media-reinvented-can-social-media-help-tackle-the-post-pandemic-mentalhealth-onslaught#!/
- Sebastian, S.A., Co, E.L., Mahtani, A., Padda, I., Anam, M., Mathew, S.S., Shahzadi, A., Niazi, M., Pawar, S., & Johal, G.. (2023, Sep). Heart Failure: Recent Advances and Breakthroughs. Disease-a-Month. Pub Status: Published. Article URL: https://doi.org/10.1016/j.disamonth.2023.101634
- Sebastian, S.A., Co, E.L., Gautham, S., Padda, I., Johal, G.. (2023, Sep). Metabolic Surgery in Improving Arterial Health in Obese Individuals. Clinical Research in Cardiology. Pub Status: Published.Article URL: https://www.sciencedirect.com/science/article/abs/pii/S0146280623007764#:~:text=In%20conclusion%2C%20metabolic%20surgery%20is,remarkable%20enhancement%20of%20arterial%20health.
- Sebastian, S.A., Co, E.L., Mehendale, M., Sudan, S., Manchanda, K., & Khan, S.. (2022, Aug). Challenges and updates in the diagnosis and treatment of infective endocarditis. Current Problems in Cardiology, 47(9), 101267. Cited in PubMed; PMID: 35636519. Pub Status: Published.Article URL: https://www.sciencedirect.com/science/article/abs/pii/S0146280622001645?via%3Dihub
- Sebastian, S.A., Co, E.L., Mehendale,M.,& Hameed, M.. (2022, Apr). Insulin analogs in the treatment of type 2 diabetes and the future perspectives. Disease-a-Month., 68(10), 1-15. Cited in PubMed; PMID: 35487767. Pub Status: Published. Article URL: https://www.sciencedirect.com/science/article/abs/pii/S0011502922001018?via%3Dihub
- Sebastian, S.A., Co, E.L., Panthangi, V., Bansal, R., Narayanan, V., Paudel, S., Raja, R., Padda, I., & Mohan, B.P. . (2023, Mar). Colonic diverticular bleeding: An update on pathogenesis and management. Disease-a-Month, N/A(N/A), N/A.Cited in PubMed; PMID: 36918300. Pub Status: Published. Article URL: https://doi.org/10.1016/j.disamonth.2023.101543
- Sebastian, S.A., Co, E.L., Panthangi, V., Jain, E., Ishak, A., Shah, Y., Vasavada, A., & Padda, I.. (2022, Aug). Postural orthostatic tachycardia syndrome (POTS): an update for clinical practice. Current Problems in Cardiology, 101384(-), -. Cited in PubMed; PMID: 36055438. Pub Status: Published. Article URL: https://www.sciencedirect.com/science/article/abs/pii/S014628062200281X?via%3Dihub
- Sebastian, S.A., Panthangi, V., Singh, K., Rayaroth, S., Gupta, A., Shantharam, D., Rasool, B.Q., Padda, I., Co, E.L., & Johal, G.(2023, Apr). Hypertrophic Cardiomyopathy: Current Treatment and Future Options. Current Problems in Cardiology, 48(4), 101552. Cited in PubMed; PMID: 36529236. Pub Status: Published. Article URL: https://www.sciencedirect.com/science/article/abs/pii/S0146280622004492
- Sudan, S., Sebastian, S.A., Co, E.L.. (2022, Jun). Fahr's disease with an atypical onset of epileptic seizure. Radiology Case Reports, 17(9), 3139-3141. Cited in PubMed; PMID: 35774054.Pub Status: Published.Article URL: https://www.sciencedirect.com/science/article/pii/S1930043322004484?via%3Dihub
- Sudan,S., Sebastian, S.A., Co, E.L., & Kaur, N.. (2022, May). Carbamazepine-induced symptomatic bradycardia in a middle-aged female: carbamazepine-induced bradycardia. Global Journal of Medical Students, 16(2), 20-3. Pub Status: Published.Article URL: https://www.thegjms.org/journal/index.php/gjms/article/view/40
- Tidd-Johnson, A., Sebastian, S.A., Co, E.L., Afaq, M., Kochhar, H., Sheikh, M., Mago, A., Poudel, S., Fernandez, J.A., Rodriguez,I.D., & Razdan, S.. (2022, Dec). Prostate cancer screening: continued controversies and novel biomarker advancements.. Current Urology, 16(4), 197-206. Cited in PubMed; PMID: 36714234.Pub Status: Published. Article URL: https://journals.lww.com/cur/Fulltext/2022/12000/Prostate_cancer_screening__Continued_controversies.2.aspx
Peer Reviewed Journal Articles/Abstracts (Other than Published)
- Sebastian, S.A., Kaiwan, O., Co, E.L., Mehendale, M., & Mohan, B.. (2023, Aug). Current Pharmacologic Options and Emerging Therapeutic Approaches for the Management of Ulcerative Colitis. Spartan Medical Research Journal. Pub Status: Accepted/In-Press.
Poster Presentation
- Co, E.L.., Sebastian, S.A., Maskey, U., Mehendale, M., Chodhury, S., & Rodriguez, I. . (2022, September 16). Hybrid closed-loop therapy as management for type 1 diabetes mellitus in pregnant patients. [Poster presented]. Women in Medicine Summit 2022/Chicago, IL, USA.
- Agolli, A., Ishak, A., Viswanathan, M., Co, E.L., & Shivakumar, J.. (2022, November 18). The oncogenic role of Epstein-Barr Virus Infection in the risk of breast cancer [Poster presented]. North American Primary Care Research Group (NAPCRG) Annual Meeting Conference/Phoenix, AZ, USA.
- Sebastian SA, Co, E.L., Sudan S, et al. (2022, September 10). Fahr’s disease with an atypical onset of epileptic seizure [Poster presented]. Kentucky-American College Cardiology 2022 Annual Meeting and Scientific Session/Louiseville, KY, USA.
- Sebastian, S.A., Co, E.L., Jain, E., Tidd-Johnson, A., Ishak, A., Chowdhury, S., Davidson, M., Gupta, R., & Michel, G.. (2022,September 10). Usefulness of carotid ultrasound screening in primary cardiovascular prevention: a systematic review [Poster presented]. Kentucky-American College Cardiology 2022 Annual Meeting and Scientific Session/Louiseville, KY, USA.
- Sebastian, S.A., Co, E.L., Jain, E., Tidd-Johnson, A., Ishak, A., Chowdhury, S., Davidson, M., Gupta, R., & Michel, G.. (2022, October 20). Usefulness of carotid ultrasound screening in primary cardiovascular prevention: a systematic review [Poster presented]. Quality Improvement and Patient Safety Symposium/Hamilton, ON, CAN.
Oral Presentation
- Co, E.L., Sebastian, S.A., Maskey, U., Mehendale, M., Chodhury, S., & Rodriguez, I. . (2022, October 20). Hybrid closed-loop therapy as management for type 1 diabetes mellitus in pregnant patients. [Oral Presentation]. Association of Philippine Physicians in America Annual Convention/Philadelphia, PA, USA.
Overview
Cavernous angioma, also known as cavernous hemangioma, cavernoma, and cerebral cavernous malformation, is a vascular malformation with still an unclear history of its first clinical discovery.
Historical Perspective
- Recognition of the first discovery of cerebrovascular angioma is still unknown. [1]
- Virchow was the first person to classify cerebrovascular malformations. Subsequent studies regarding the classification of this pathology were conducted mostly in Germany.[1]
- The advent of cerebral angiography paved the way for a better understanding of the context of "cryptic" or occult vascular malformations. [1]
- McCormick clarified the current pathological features of cavernous angiomas, which are now being correlated with MRI findings. [1]
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