Cholera (patient information)
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What is Cholera?
Cholera is an acute, diarrheal illness caused by infection of the intestine with the bacterium Vibrio cholerae. The infection is often mild or without symptoms, but sometimes it can be severe. Approximately one in 20 infected persons has severe disease characterized by profuse watery diarrhea, vomiting, and leg cramps. In these persons, rapid loss of body fluids leads to dehydration and shock. Without treatment, death can occur within hours.
What are the symptoms of Cholera?
The following is a list of symptoms commonly associated with people who have developed cholera:
- Abdominal cramps
- Dry mucus membranes or mouth
- Dry skin
- Excessive thirst
- Glassy or sunken eyes
- Lack of tears
- Lethargy
- Low urine output
- Nausea
- Rapid dehydration
- Rapid pulse
- Sunken "soft spots" (fontanelles) in infants
- Unusual tiredness
- Vomiting
- Watery diarrhea that starts suddenly and has a "fishy" odor
What are the causes of Cholera?
Cholera is caused by the bacterium Vibrio cholerae. The bacteria releases a toxin that causes increased release of water in the intestines, which produces severe diarrhea.
Cholera occurs in places with poor sanitation, crowding, war, and famine. Common locations for cholera include:
- Africa
- Asia
- India
- Mexico
- South and Central America
People get the infection by eating or drinking contaminated food or water.
A type of vibrio bacteria also has been associated with shellfish, especially raw oysters.
Risk factors include:
- Exposure to contaminated or untreated drinking water
- Living in or traveling to areas where there is cholera
Who is at risk for Cholera?
How to know you have Cholera?
Tests that may be done include:
- Blood culture
- Stool culture
When to seek urgent medical care
Call your health care provider if :
- You develop severe watery diarrhea
- You have signs of dehydration, including:
- Dry mouth
- Dry skin
- "Glassy" eyes
- Lethargy
- No tears
- Rapid pulse
- Reduced or no urine
- Sunken eyes
- Thirst
- Unusual sleepiness or tiredness
Treatment options
Cholera can be simply and successfully treated by immediate replacement of the fluid and salts lost through diarrhea. Patients can be treated with oral rehydration solution, a prepackaged mixture of sugar and salts to be mixed with water and drunk in large amounts. This solution is used throughout the world to treat diarrhea. Severe cases also require intravenous fluid replacement. With prompt rehydration, fewer than 1% of cholera patients die.
Antibiotics shorten the course and diminish the severity of the illness, but they are not as important as rehydration. Persons who develop severe diarrhea and vomiting in countries where cholera occurs should seek medical attention promptly.
Diseases with similar symptoms
Where to find medical care for Cholera
Directions to Hospitals Treating Cholera
Prevention of Cholera
What to expect (Outlook/Prognosis)
Severe dehydration can cause death. Given adequate fluids, most people will make a full recovery.
Possible Complications
- Severe dehydration
- Death