Pericarditis laboratory studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Inflammatory markers

The following inflammatory markers are often elevated:

The following markers of myonecrosis are elevated:

Creatine Kinase: Acute pericarditis is associated with a modest increase in serum creatine kinase MB (CK-MB)^[1]^[2]
Cardiac troponin I (cTnI)^[3]^[4].
LDH: depends on the extent of myocardial involvement
Serum myoglobin: normal (but not always, usually rises with increased ST segment deviation
Gallium-67 scanning may help identify inflammatory and leukemic infiltrations

↑ Spodick DH (2003). "Acute pericarditis: current concepts and practice". JAMA. 289 (9): 1150–3. doi:10.1001/jama.289.9.1150. PMID 12622586.
↑ Karjalainen J, Heikkila J (1986). ""Acute pericarditis": myocardial enzyme release as evidence for myocarditis". Am Heart J. 111 (3): 546–52. doi:10.1016/0002-8703(86)90062-1. PMID 3953365.
↑ Bonnefoy E, Godon P, Kirkorian G, Fatemi M, Chevalier P, Touboul P (2000). "Serum cardiac troponin I and ST-segment elevation in patients with acute pericarditis". Eur Heart J. 21 (10): 832–6. doi:10.1053/euhj.1999.1907. PMID 10781355.
↑ Imazio M, Demichelis B, Cecchi E, Belli R, Ghisio A, Bobbio M, Trinchero R (2003). "Cardiac troponin I in acute pericarditis". J Am Coll Cardiol. 42 (12): 2144–8. doi:10.1016/j.jacc.2003.02.001. PMID 14680742.