Xanthelasma

Xanthelasma
ICD-10	H02.6
ICD-9	374.51
DiseasesDB	28519
MedlinePlus	001447
eMedicine	oph/610

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Overview

Xanthelasma (or xanthelasma palpebrarum) is a sharply demarcated yellowish collection of cholesterol underneath the skin, usually on or around the eyelids. Although not harmful or painful, these minor growths may be disfiguring and can be removed. The plural is "xanthelasmata". They are common in people of Asian extraction and those from the Mediterranean region. Xanthelasmata can be removed with trichloroacetic acid peel, surgery, lasers or cryotherapy. Removal can cause scarring and pigment changes, but it is unusual after treatment with trichloroacetic acid. Because of the hereditary component, they may or may not indicate high blood levels of cholesterol. Where there is no family history of xanthelasmata they usually indicate high cholesterol and may correlate with a risk of atheromatous disease (cholesterol building up in arteries). The root of the word is from Greek xanthos, ξανθος, "yellow".

Associations

• High cholesterol levels (specifically familial hypercholesterolemia)
• Primary biliary cirrhosis
• Menopause
• Diabetes

See also

• Xanthoma (similar collections of cholesterol around tendons)

External links

• Beth Israel Deaconess Medical Center: Xanthelasma
• MedlinePlus Encyclopedia Xanthelasma and Xanthoma
• Xanthelasma at eMedicine
• UAB

References

• Lang, Gerhard K Ophthalmology Thieme. Stuttgart. 2000.