Chronic stable angina spinal cord stimulation
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Chronic stable angina Microchapters | ||
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Classification | ||
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Differentiating Chronic Stable Angina from Acute Coronary Syndromes | ||
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Diagnosis | ||
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Alternative Therapies for Refractory Angina | ||
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Discharge Care | ||
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Guidelines for Asymptomatic Patients | ||
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Case Studies | ||
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Chronic stable angina spinal cord stimulation On the Web | ||
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to Hospitals Treating Chronic stable angina spinal cord stimulation | ||
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Risk calculators and risk factors for Chronic stable angina spinal cord stimulation | ||
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3] Phone:617-632-7753; Cafer Zorkun, M.D., Ph.D. [4]; Associate Editor(s)-In-Chief: John Fani Srour, M.D.; Jinhui Wu, M.D.; Lakshmi Gopalakrishnan, M.B.B.S.
Overview
Spinal cord stimulation (SCS) uses an implanted device with an electrode tip that extends into the dorsal epidural space, usually at the C7-T1 level.
Mechanism of Benefit
- Spinal cord stimulation uses an implantable device with a atimulating electrode placed in the epidural space, usually at the level of C7-T1 and provides analgesia secondary to neuromodulation.
- SCS benefits secondary to:
- Decrease in the neurotransmission of painful stimuli,
- Increase in the release of endogenous opiates,
- Redistributes myocardial blood flow to ischemic areas.
Indication
In patients with chronic stable angina refractory to medical therapy, PCI, and/or surgical therapy (more data are still needed and therefore, spinal cord stimulation should be only considered when other treatment options have failed).
Supportive trial data
Several observational studies have reported success rates of up to 80% in decreasing anginal frequency and severity.
- Efficacy of spinal cord stimulation as a treatment for chronic intractable angina, was studied for 6 weeks in 13 treated patients versus 12 control patients with chronic angina. At 6-week follow-up, in comparison to the control group, the treated group demonstrated significant increase in the exercise duration (P=0.03) and the time to angina (P=0.01); and a significant reduction in the incidence of anginal attacks and sublingual nitrate consumption (P=0.01) and in the incidence of ischemic episodes on 48-hour electrocardiogram (P=0.04). The ST segment depression on the exercise electrocardiogram decreased at comparable workload (P=0.01) with a significant increase in the perceived quality of life (P=0.03). Thus, the study concluded that spinal cord stimulation is an effective alternative the management of chronic intractable angina pectoris, and that its effect was exerted through anti-ischemic action.[1]
ACC/AHA Guidelines- Spinal Cord Stimulation (DO NOT EDIT)[2][3]
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Sources
- The ACC/AHA/ACP–ASIM Guidelines for the Management of Patients With Chronic Stable Angina [2]
- TheACC/AHA 2002 Guideline Update for the Management of Patients With Chronic Stable Angina [3]
- Guidelines on the management of stable angina pectoris: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology [4]
- The 2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina [5]
References
- ↑ Hautvast RW, DeJongste MJ, Staal MJ, van Gilst WH, Lie KI (1998) Spinal cord stimulation in chronic intractable angina pectoris: a randomized, controlled efficacy study. Am Heart J 136 (6):1114-20. PMID: 9842028
- ↑ 2.0 2.1 Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, Gardin JM et al. (1999)guidelines for the management of patients with chronic stable angina: executive summary and recommendations. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Chronic Stable Angina).Circulation 99 (21):2829-48. PMID: 10351980
- ↑ 3.0 3.1 Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS et al. (2003) ACC/AHA 2002 guideline update for the management of patients with chronic stable angina--summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Chronic Stable Angina). Circulation 107 (1):149-58. PMID: 12515758
- ↑ Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F; et al. (2006). [url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16735367 [1] "Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology"] Check
|url=value (help). Eur Heart J. 27 (11): 1341–81. doi:10.1093/eurheartj/ehl001. PMID 16735367. - ↑ Fraker TD, Fihn SD, Gibbons RJ, Abrams J, Chatterjee K, Daley J et al. (2007)2007 chronic angina focused update of the ACC/AHA 2002 Guidelines for the management of patients with chronic stable angina: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to develop the focused update of the 2002 Guidelines for the management of patients with chronic stable angina. Circulation 116 (23):2762-72.[2] PMID: 17998462