Guidewire coatings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The distal half (the distal 30-35 cm) of coronary guidewires are coated with slippery (lubricious) materials to reduce the friction of the guidewire as it crosses the blockage in the coronary artery and to also facilitate the passage and delivery of intracoronary devices down the artery.

Classification Of Lubricious Coatings

Hydrophilic

• Attracts water

  It is applied over polymer or stainless steel (including tip coils)

  Thin, non-slippery solid when dry, needs lubrication to perform

  Becomes a gel when wet

  Reduces friction

  Increases trackability

Commonly used Guidewire Coatings

• PTFE (Polytetrafluroehylene) is the most common coating
• Teflon
• Silicone
• Pro/Pel®, (Medtronic)
• Hydro-track® (Medtronic)
• Hydro-coat (Abbott vascular)

HYDROPHOBIC COATING

• repels water
• Silicone on working area of wire, excluding tip
• No actuation/wetting required
• Reduces friction
• Increases trackability

Platinum in the tip for radio-opacity. (usually 3-25 cm length at the tip)