Breast cancer bone metastasis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor(s)-In-Chief: Jack Khouri

Overview

Bone is the most common site of breast cancer recurrence [1], [2]. A Skeletal-Related event (sre)is defined as any of the following:

  • pathologic fracture,
  • a requirement for surgical intervention and palliative radiotherapy to bone lesions,
  • spinal cord compression
  • hypercalcemia of malignancy

SRE cause major morbidity, decrease survival and reduce quality of life.

References

  1. ↑ Coleman RE (2006). "Clinical features of metastatic bone disease and risk of skeletal morbidity". Clin Cancer Res. 12 (20 Pt 2): 6243s–6249s. doi:10.1158/1078-0432.CCR-06-0931. PMID 17062708.
  2. ↑ Coleman RE, Rubens RD (1987). "The clinical course of bone metastases from breast cancer". Br J Cancer. 55 (1): 61–6. PMC 2001575. PMID 3814476.

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