Saphenous vein graft

Saphenous vein graft
Saphenous vein grafts for coronary arteries

WikiDoc Resources for Saphenous vein graft
Articles
Most recent articles on Saphenous vein graft Most cited articles on Saphenous vein graft Review articles on Saphenous vein graft Articles on Saphenous vein graft in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Saphenous vein graft Images of Saphenous vein graft Photos of Saphenous vein graft Podcasts & MP3s on Saphenous vein graft Videos on Saphenous vein graft
Evidence Based Medicine
Cochrane Collaboration on Saphenous vein graft Bandolier on Saphenous vein graft TRIP on Saphenous vein graft
Clinical Trials
Ongoing Trials on Saphenous vein graft at Clinical Trials.gov Trial results on Saphenous vein graft Clinical Trials on Saphenous vein graft at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Saphenous vein graft NICE Guidance on Saphenous vein graft NHS PRODIGY Guidance FDA on Saphenous vein graft CDC on Saphenous vein graft
Books
Books on Saphenous vein graft
News
Saphenous vein graft in the news Be alerted to news on Saphenous vein graft News trends on Saphenous vein graft
Commentary
Blogs on Saphenous vein graft
Definitions
Definitions of Saphenous vein graft
Patient Resources / Community
Patient resources on Saphenous vein graft Discussion groups on Saphenous vein graft Patient Handouts on Saphenous vein graft Directions to Hospitals Treating Saphenous vein graft Risk calculators and risk factors for Saphenous vein graft
Healthcare Provider Resources
Symptoms of Saphenous vein graft Causes & Risk Factors for Saphenous vein graft Diagnostic studies for Saphenous vein graft Treatment of Saphenous vein graft
Continuing Medical Education (CME)
CME Programs on Saphenous vein graft
International
Saphenous vein graft en Espanol Saphenous vein graft en Francais
Business
Saphenous vein graft in the Marketplace Patents on Saphenous vein graft
Experimental / Informatics
List of terms related to Saphenous vein graft

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Jason C. Choi, M.D.; Xin Yang, M.D.

Overview

Since Rene Favaloro first described it in 1967, coronary artery revascularization with saphenous veins (saphenous vein grafts or SVGs) has become a surgical standard for treatment of coronary artery disease. When a native coronary artery is obstructed, the sutured graft provides a connection between the aorta and the coronary artery beyond the area of obstruction. The procedure is repeated on all the coronary artery segments that are significantly diseased.

The vein is often removed by cardiac surgeons and used for autotransplantation in coronary artery bypass operations, when arterial grafts are not available or many grafts are required, such as in a triple bypass or quadruple bypass.

Clinical Trials

• Radial Artery Versus Saphenous Vein Grafts in Coronary Artery Bypass Surgery
• The RETRIEVE Study: Use of the FiberNet Embolic Protection System in Saphenous Vein Grafts
• The SOS (Stenting Of Saphenous Vein Grafts) Trial
• Symbiot III: A Prospective Randomized Trial Evaluating the Symbiot Covered Stent System in Saphenous Vein Grafts
• Comparison of Safety and Efficacy of Two Different Drug Eluting Stents Implanted Into Saphenous Vein Grafts
• Evaluating the Role of Thrombin in Saphenous Vein Graft Failure After Heart Bypass Surgery
• Acupuncture and Post-Surgical Wound Healing
• RRISC Study: Reduction of Restenosis In Saphenous Vein Grafts With Cypher Sirolimus-Eluting Stent.
• Treatment of Moderate Vein Graft Lesions With Paclitaxel Drug Eluting Stents: The VELETI Trial
• Trial of Clopidogrel After Surgery for Coronary Artery Disease (CASCADE Trial)
• Multicentre Radial Artery Patency Study: 5 Year Results
• Study to Test the Efficacy and Safety of Drug Eluting vs. Bare-Metal Stents for Saphenous Vein Graft Interventions (BASKETSAVAGE)
• Vein-Coronary Atherosclerosis And Rosiglitazone After Bypass Surgery: The VICTORY Trial
• Copenhagen Arterial Revascularization Randomized Patency and Outcome Trial (CARRPO)
• The SOS (Stenting Of Saphenous Vein Grafts) Trial
• The eSVS (TM) Mesh External Saphenous Vein Support Trial

Additional Resources

• S. A. Hassantash, B. Bikdeli, S. Kalantarian, M. Sadeghian, and H. Afshar Pathophysiology of Aortocoronary Saphenous Vein Bypass Graft Disease Asian Cardiovasc Thorac Ann, August 1, 2008; 16(4): 331 - 336.

• A. Coolong, D. S. Baim, R. E. Kuntz, A. J. O'Malley, S. Marulkar, D. E. Cutlip, J. J. Popma, and L. Mauri. Saphenous Vein Graft Stenting and Major Adverse Cardiac Events: A Predictive Model Derived From a Pooled Analysis of 3958 Patients. Circulation, February 12, 2008; 117(6): 790 - 797.

• R. F. Padera Jr. and F. J. Schoen. Pathology of Cardiac Surgery Card. Surg. Adult, January 1, 2008; 3(2008): 111 - 178.

• E. Gongora and T. M. Sundt III. Myocardial Revascularization with Cardiopulmonary Bypass. Card. Surg. Adult, January 1, 2008; 3(2008): 599 - 632.

• P. Widimsky, Z. Straka, P. Stros, K. Jirasek, J. Dvorak, J. Votava, L. Lisa, T. Budesinsky, M. Kolesar, T. Vanek, et al. One-Year Coronary Bypass Graft Patency: A Randomized Comparison Between Off-Pump and On-Pump Surgery Angiographic Results of the PRAGUE-4 Trial Circulation, November 30, 2004; 110 (22): 3418 - 3423.

• M. A. Hlatky, D. B. Boothroyd, K. A. Melsop, M. M. Brooks, D. B. Mark, B. Pitt, G. S. Reeder, W. J. Rogers, T. J. Ryan, P. L. Whitlow, et al. Medical Costs and Quality of Life 10 to 12 Years After Randomization to Angioplasty or Bypass Surgery for Multivessel Coronary Artery Disease Circulation, October 5, 2004; 110 (14): 1960 - 1966.

• J. G. Lobo Filho, M. C. d. A. Leitao, and A. J. d. V. Forte Studying the lumen in composite Y internal thoracic artery-saphenous vein grafts J. Thorac. Cardiovasc. Surg., September 1, 2004; 128(3): 490 - 491.

• E. McGregor, L. Kempster, R. Wait, M. Gosling, M. J. Dunn, and J. T. Powell. F-actin Capping (CapZ) and Other Contractile Saphenous Vein Smooth Muscle Proteins Are Altered by Hemodynamic Stress: a proteomic approach Mol. Cell. Proteomics, February 1, 2004; 3(2): 115 - 124.

• M. Endo, Y. Tomizawa, and H. Nishida Bilateral Versus Unilateral Internal Mammary Revascularization in Patients with Diabetes Circulation, September 16, 2003; 108(11): 1343 - 1349.

• T. D. Rea, M. Crouthamel, M. S. Eisenberg, L. J. Becker, and A. R. Lima. Temporal Patterns in Long-Term Survival After Resuscitation From Out-of-Hospital Cardiac Arrest Circulation, September 9, 2003; 108(10): 1196 - 1201.

• M. Hilker, T. Langin, U. Hake, F.-X. Schmid, W. Kuroczynski, H.-A. Lehr, H. Oelert, and M. Buerke Gene expression profiling of human stenotic aorto-coronary bypass grafts by cDNA array analysis Eur. J. Cardiothorac. Surg., April 1, 2003; 23(4): 620 - 625.

• J. L. Sperry, C. B. Deming, C. Bian, P. L. Walinsky, D. A. Kass, F. D. Kolodgie, R. Virmani, A. Y. Kim, and J. J. Rade Wall Tension Is a Potent Negative Regulator of In Vivo Thrombomodulin Expression Circ. Res., January 10, 2003; 92(1): 41 - 47.

• F. J. Schoen and R. F. Padera Jr. Cardiac Surgical Pathology Card. Surg. Adult, January 1, 2003; 2(2003): 119 - 185.

• A. Y. Kim, P. L. Walinsky, F. D. Kolodgie, C. Bian, J. L. Sperry, C. B. Deming, E. A. Peck, J. G. Shake, G. B. Ang, R. H. Sohn, et al. Early Loss of Thrombomodulin Expression Impairs Vein Graft Thromboresistance: Implications for Vein Graft Failure Circ. Res., February 8, 2002; 90(2): 205 - 212.

• K. B. Kim, C. Lim, C. Lee, I.-H. Chae, B.-H. Oh, M.-M. Lee, and Y.-B. Park Off-pump coronary artery bypass may decrease the patency of saphenous vein grafts Ann. Thorac. Surg., September 1, 2001; 72(3): S1033 - 1037.

• Z. Yang, T. Kozai, B. van de Loo, H. Viswambharan, M. Lachat, M. I. Turina, T. Malinski, and T. F. Luscher. HMG-CoA reductase inhibition improves endothelial cell function and inhibits smooth muscle cell proliferation in human saphenous veins J. Am. Coll. Cardiol., November 1, 2000; 36(5): 1691 - 1697.

• H. Hirose, A. Amano, S. Yoshida, A. Takahashi, N. Nagano, and T. Kohmoto Coronary Artery Bypass Grafting in the Elderly Chest, May 1, 2000; 117(5): 1262 - 1270.

• D. R. Holmes Jr and P. B. Berger. Percutaneous Revascularization of Occluded Vein Grafts : Is It Still a Temptation to Be Resisted? Circulation, January 12, 1999; 99(1): 8 - 11.

• Y. K. Wong, M. Thomas, V. Tsang, P. J. Gallagher, and M. E. Ward. The prevalence of Chlamydia pneumoniae in atherosclerotic and nonatherosclerotic blood vessels of patients attending for redo and first time coronary artery bypass graft surgery. J. Am. Coll. Cardiol., January 1, 1999; 33(1): 152 - 156.

• F. D. Loop Coronary artery surgery: the end of the beginning Eur. J. Cardiothorac. Surg., December 1, 1998; 14(6): 554 - 571.

• Z. G. Zhu, H.-H. Li, and B.-R. Zhang. Expression of Endothelin-1 and Constitutional Nitric Oxide Synthase Messenger RNA in Saphenous Vein Endothelial Cells Exposed to Arterial Flow Shear Stress Ann. Thorac. Surg., November 1, 1997; 64(5): 1333 - 1338.

• A. Y. Kim, P. L. Walinsky, F. D. Kolodgie, C. Bian, J. L. Sperry, C. B. Deming, E. A. Peck, J. G. Shake, G. B. Ang, R. H. Sohn, et al. Early Loss of Thrombomodulin Expression Impairs Vein Graft Thromboresistance: Implications for Vein Graft Failure. Circ. Res., February 8, 2002; 90(2): 205 - 212.

Related Chapters

• CABG
• Hybrid bypass
• Off-pump coronary artery bypass surgery (OPCAB)
• Minimally invasive direct coronary artery bypass surgery (MIDCAB)

External Links

• Advances in Cardiovascular Surgery and Cardiothoracic Surgical Procedures
• CTSNet: The Cardiothoracic Surgery Network
• Yale: Introduction to Cardiothoracic Imaging