Granulocytosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. [2]
Overview
- Granulocytosis is defined as the presence of an increased number of granulocytes, a category of white blood cells present in the peripheral blood. Often, the word refers to an increased neutrophil granulocyte count, as neutrophils are the main granulocytes.
- An increase in eosinophil granulocyte is known as eosinophilia.
- Granulocytosis can be a feature of a number of diseases:
- Infection, especially bacterial
- Malignancy, most notably leukemia (it is the main feature of chronic myelogenous leukemia, CML)
- Autoimmune disease
- In cardiovascular disease, increased white blood cell counts have been shown to indicate a worse prognosis.