2C (psychedelics)

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2C is a general name for the family of psychedelic phenethylamines containing methoxy groups on the 2 and 5 positions of the benzene ring. Most of these compounds also carry lipophilic substituents at the 4 position, usually resulting in more potent and more metabolically stable and longer acting compounds. Most of the currently known 2C compounds were first synthesized by Alexander Shulgin in the 1970's and 1980's, and published in his book, PiHKAL (Phenethylamines I Have Known And Loved). Dr. Shulgin also invented the term 2C, being an acronym for the 2 carbon atoms between the benzene ring and the amino group (the amphetamine counterparts are sometimes known as 3C's) .

File:2c general structure.svg

General structure of a 2C compound

File:2C-T-7.svg

Chemical structure of 2C-T-7

File:2C-T-21.svg

Chemical structure of 2C-T-21

Nomenclature	R3	R4	2D Structure	3D Structure	Revolving Structure
2C-B	H	Br	File:2C-B.svg	File:2C-B-3d-sticks.png	File:2C-B animation.gif
2C-C	H	Cl	File:2C-C.png	File:2C-C-3d-sticks.png	File:2C-C animation.gif
2C-D	H	CH3	File:2C-D.png	File:2C-D-3d-sticks.png	File:2C-D animation.gif
2C-E	H	CH2CH3	File:2C-E.png	File:2C-E-3d-sticks.png	File:2C-E animation.gif
2C-F	H	F	File:2C-F.png	File:2C-F-3d-sticks.png	File:2C-F animation.gif
2C-G	CH3	CH3	File:2C-G.png	File:2C-G-3d-sticks.png	File:2C-G animation.gif
2C-G-3	(CH2)3		File:2C-G-3.png
2C-G-4	(CH2)4		File:2C-G-4.png
2C-G-N	(CH)4		File:2C-G-N.png
2C-H	H	H	File:2C-H.png	File:2C-H-3d-sticks.png	File:2C-H animation.gif
2C-I	H	I	File:2C-I.png	File:2C-I-3d-sticks.png	File:2C-I animation.gif
2C-N	H	NO2		File:2C-N-3d-sticks.png	File:2C-N animation.gif
2C-O	H	OCH3	File:2C-O.png		File:2C-O animation.gif
2C-O-4	H	OCH(CH3)2	File:2C-O-4.png		File:2C-O-4 animation.gif
2C-P	H	CH2CH2CH3	File:2C-P.png	File:2C-P-3d-sticks.png	File:2C-P animation.gif
2C-SE	H	SeCH3	File:2C-SE.png	File:2C-SE-3d-sticks.png	File:2C-Se animation.gif
2C-T	H	SCH3	File:2C-T.png		File:2C-T animation.gif
2C-T-2	H	SCH2CH3	File:2C-T-2.png
2C-T-4	H	SCH(CH3)2	File:2C-T-4.png	File:2C-T-4-3d-sticks.png
2C-T-7	H	S(CH2)2CH3	File:2C-T-7.png	File:2C-T-7-3d-sticks.png
2C-T-8	H	SCH2CH(CH2)2	File:2C-T-8.png	File:2C-T-8-3d-sticks.png
2C-T-9	H	SC(CH3)3	File:2C-T-9.png	File:2C-T-9-3d-sticks.png
2C-T-13	H	S(CH2)2OCH3	File:2C-T-13.png	File:2C-T-13-3d-sticks.png
2C-T-15	H	SCH(CH2)2	File:2C-T-15.png	File:2C-T-15-3d-sticks.png
2C-T-17	H	SCH(CH3)CH2CH3	File:2C-T-17.png	File:2C-T-17-3d-sticks.png
2C-T-21	H	S(CH2)2F	File:2C-T-21.png	File:2C-T-21-3d-sticks.png
2C-TFM	H	CF3	File:2C-TFM.png		File:2C-TFM animation.gif

See also

• Substituted amphetamines

External links

• Book II of PiHKAL.

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