Fosfomycin

Fosfomycin

File:Fosfomycin skeletal.svg
Clinical data
Pregnancy category	US: B (No risk in non-human studies)
Routes of administration	Oral
ATC code	J01XX01 (WHO)
Legal status
Legal status	US: ℞-only
Pharmacokinetic data
Bioavailability	30–37% (oral, fosfomycin tromethamine); varies with food intake
Protein binding	Nil
Metabolism	Nil
Elimination half-life	5.7 hours (mean)
Excretion	Renal and fecal, unchanged
Identifiers
IUPAC name [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid
CAS Number	23155-02-4 78964-85-9 (tromethamine)
PubChem CID	446987
DrugBank	APRD00987
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C3H7O4P
Molar mass	138.059 g/mol

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Fosfomycin (also known as phosphomycin and phosphonomycin) is a broad-spectrum antibiotic produced by certain Streptomyces species. It is indicated in the treatment of urinary tract infections. It is usually administered as fosfomycin tromethamine, trade name Monurol.

Fosfomycin is usually administered as a single dose.

See also

• Fosmidomycin

External links

• Fosfomycin information at RxList

Template:Other antibacterials