Gonadotropins

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

• Gonadotropins are the hormones capable of promoting gonadal growth and function
• Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) are examples of gonadotropins

Reference Range in Grown-Up Women
Follicle Phase
LH	1.8-13.4 mU/ml
FSH	3-12 mU/ml
Periovulatory Phase
LH	15.6-78.9 mU/ml
FSH	8-22 mU/ml
Luteal Phase
LH	0.7-19.4 mU/ml
Postmenopausal
LH	> 50 mU/ml
FSH	12-30 mU/ml
Reference Range in Men
LH	1.5-9.2 mU/ml
FSH	1-14 mU/ml

Differential Diagnosis

Increased FSH and LH

• After radiation therapy
• Chemotherapeutic therapy
• Climacterium praecox
• During menopause or postmenopausal
• Gonadal dysgenesis
• Primely hypogonadism
• Swyer-James Syndrome
• Turner's Syndrome

Reduced FSH and LH

• Anorexia Nervosa
• Hyperprolactinemia
• Progestogen negative amenorrhea
• Traumatic or tumorous damage of the pituitary or the hypothalamus

Reduced FSH/LH Quotient

• Hyperandrogenic ovarial insufficiency
• Polycystic ovary syndrome

Acknowledgements

The content on this page was first contributed by Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]

List of contributors:

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