Mixed disorder of acid-base balance
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Template:DiseaseDisorder infobox In a mixed disorder of acid-base balance more than one of the following four primary acid base disorders is occurring in the patient at the same time:
condition | pH | carbon dioxide | compensation |
metabolic acidosis | down | down | respiratory |
respiratory acidosis | down | up | renal |
metabolic alkalosis | up | up | respiratory |
respiratory alkalosis | up | down | renal |
(Exception: A person cannot have both a respiratory acidosis and a respiratory alkalosis at the same time.)
In contrast, with a simple acid base disorder, there is only one of the four primary acid base disorders present.
The patient can have an acidosis and alkosis at the same time that partially counteract each other, or there can be two different conditions effecting the pH in the same direction. The phrase "mixed acidosis", for example, refers to metabolic acidosis in conjunction with respiratory acidosis.
There is actually an easy way to identify if the Acid-Base balance disorder is Metabolic or Respiratory in origin.
- If the pH and Carbon dioxide levels are either both increased or decreased, then it is Metabolic.
- If the pH level is opposite to that of the Carbon dioxide level or vice versa, then it is Respiratory.
Determining if it is acidosis or alkalosis depends upon the pH of the blood which is normally regulated between pH 7.35 and 7.45.
- If pH is above 7.45, then an alkalemia is present - this indicates the presence of an alkalosis.
- If pH is below 7.35, then an acidemia is present - this indicates the presence of an acidosis.