Legionellosis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Complete blood count and differential count - lymphocytopenia and rarely pancytopenia
Sputum Gram staining - gram negative rods
Urine antigen test - the urine antigen test is simple, quick, and very reliable; however it will only detect Legionella pneumophila serogroup #1. Also the urine antigen test will not identify the specific subtyping so it cannot be used to match the patient with the environmental source of infection.
Antibody test - compare antibody levels to Legionella in two blood samples obtained 3 to 6 weeks apart.
Serum electrolytes - hyponatremia
Liver function tests - elevated bilirubin levels
Urinalysis - proteinuria