Teplizumab

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Template:Drugbox-mab Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Teplizumab is a monoclonal antibody which it is used as an immunosuppressive drug. It is a humanized Fc-engineered monoclonal antibody also known as MGA031 and hOKT3γ1(Ala-Ala)[1][2].

References

  1. Woodle, E.S., Bluestone, J., Zivin, R., Jolliffe, L., Auger, J., Xu, D., and J. Thistlethwaite. "Humanized, nonmitogenic OKT3 antibody, huOKT3 gamma(Ala-Ala): initial clinical experience." (1998) Transplant Proc. 30:1369-1370
  2. Brown, W.M. "Anti-CD3 antibody MacroGenics Inc." (2006) Curr Opin Investig Drugs, 74:381-8.

External links

  • [3] MacroGenics, Inc.

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