Asherman's syndrome natural history, complications and prognosis
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Editor(s)-in-Chief: C. Michael Gibson, M.S.,M.D. [1] Phone:617-632-7753; Canan S Fornusek, Ph.D.; Associate Editor-In-Chief: M.Umer Tariq [2]
Overview
Complications
Depending on the degree of severity, Asherman's syndrome may result in infertility, repeated miscarriages, pain from trapped blood, and high risk pregnancies [1](see Prognoses below). There is evidence that left untreated, the obstruction of menstrual flow resulting from scarring can lead to endometriosis[2].
Asherman's can also result from other pelvic surgeries including Cesarean section[3], removal of fibroid tumours (myomectomy) and from other causes such as IUDs, pelvic irradiation, schistosomiasis[4] and genital tuberculosis[5]. Chronic endometritis from genital tuberculosis is a significant cause of severe IUA in the developing world, often resulting in total obliteration of the uterine cavity which is difficult to treat [6].
References
- ↑ Valle RF, and Sciarra JJ (1988). "Intrauterine adhesions: Hystreoscopic diagnosis, classification, treatment and reproductive outcome". . Am J Obstet. 158 (6Pt1): 1459–1470. PMID 3381869.
- ↑ Buttram VC, Turati, G (1977). "Uterine synechiae: variations in severity and some conditions which may be conducive to severe adhesions". Int J Fertil. 22 (2): 98–103. PMID 20418.
- ↑ Rochet Y, Dargent D, Bremond A, Priou G, Rudigoz RC (1979). "The obstetrical outcome of women with surgically treated uterine synechiae (in French)". J Gynecol Obstet Biol Reprod. 8 (8): 723–726. PMID 553931.
- ↑ Krolikowski A, Janowski K, Larsen JV. (1995). "Asherman syndrome caused by schistosomiasis". Obstet Gynecol. 85 (5Pt2): 898–9. doi:10.1016/0029-7844(94)00371-J. PMID 7724154.
- ↑ Netter AP, Musset R, Lambert A Salomon Y (1956). "Traumatic uterine synechiae: a common cause of menstrual insufficiency, sterility, and abortion". Am J Obstet Gynecol. 71 (2): 368–75. PMID 13283012.
- ↑ Bukulmez O, Yarali H, Gurgan T. (1999). "Total corporal synechiae due to tuberculosis carry a very poor prognosis following hysteroscopic synechialysis". Hum Reprod. 14 (8): 1960–1961. doi:10.1093/humrep/14.8.1960. PMID 10438408.