Splenic infarction medical therapy
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Splenic infarction Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
Surgery is indicated only in the presence of complications. Otherwise, the infarcted spleen can be left in situ, and the patient is observed. Due to the rarity of this disorder and the largely anecdotal character of many reports, the roles of antibiotics and antiplatelet agents (for the treatment of thrombocytosis) have not been formally addressed. Similarly, no scientifically supported information exists regarding the possible increase in susceptibility to overwhelming postsplenectomy sepsis in these patients.
The principal mainstay of medical therapy is analgesia with either narcotics or nonsteroidal anti-inflammatory agents.
In one series of 59 patients, mortality amounted to 5%.[1] Complications include a ruptured spleen, hemorrhage, splenic abscess (for example, if the underlying cause is endocarditis) or pseudocyst formation. Splenectomy may be warranted for persistent pseudocysts due to the high risk of subsequent rupture.[2]
References
- ↑ Nores M, Phillips EH, Morgenstern L, Hiatt JR (1998). "The clinical spectrum of splenic infarction". Am Surg. 64 (2): 182–8. PMID 9486895. Unknown parameter
|month=ignored (help) - ↑ Pachter HL, Hofstetter SR, Elkowitz A, Harris L, Liang HG (1993). "Traumatic cysts of the spleen--the role of cystectomy and splenic preservation: experience with seven consecutive patients". J Trauma. 35 (3): 430–6. PMID 8371303. Unknown parameter
|month=ignored (help)