Human parainfluenza viruses pathophysiology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Pathophysiology

Repeated infection throughout the life of the host is not uncommon. Symptoms of later breakouts include upper respiratory tract illness as in a cold and sore throat. The incubation period of all four serotypes is 1 to 7 days. Parainfluenza viruses can be detected via cell culture, immunofluorescent microscopy, and PCR. Though no vaccines currently exist, research into vaccines for HPIV-1, -2, and -3 is underway. Parainfluenza viruses last only a few hours in the environment and are inactivated by soap and water.