Cholesterol emboli syndrome medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
Treatment of an episode of cholesterol emboli is generally symptomatic, i.e. it deals with the symptoms and complications but cannot reverse the phenomenon itself.[1] In kidney failure resulting from cholesterol crystal emboli, statins have been shown to halve the risk of requiring hemodialysis.[2]
- No definitive therapy at this time; supportive care, fluids
- The role of anticoagulation is not clear – some of advocated anticoagulation and others have warned against it.
- Some have advocated lipid-lowering agents.
- Unclear role for glucocorticoids, even when significant eosinophilia is present
- Anecdotal case reports have reported improvement