Focal segmental glomerulosclerosis (patient information)
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Focal segmental glomerulosclerosis |
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Where to find medical care for Focal segmental glomerulosclerosis? |
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Focal segmental glomerulosclerosis On the Web |
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Directions to Hospitals Treating Focal segmental glomerulosclerosis |
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Risk calculators and risk factors for Focal segmental glomerulosclerosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]
Overview
Focal segmental glomerulosclerosis is scar tissue that forms in parts of the kidney called glomeruli. The glomeruli serve as filters, helping rid the body of unnecessary or harmful substances. Each kidney has thousands of glomeruli. One glomeruli is called a glomerulus.
"Focal" means that some of the glomeruli become scarred, while others remain normal. "Segmental" means that only part of an individual glomerulus is damaged.
What are the symptoms of Focal segmental glomerulosclerosis?
- Foamy urine (from excess protein in the urine)
- Poor appetite
- Swelling, called generalized edema, from fluids held in the body
- Weight gain
What causes Focal segmental glomerulosclerosis?
The cause of focal segmental glomerulosclerosis is usually unknown.
The condition affects both children and adults. Men and boys are affected slightly more often than women and girls, and it also occurs more often in African Americans. Focal segmental glomerulosclerosis causes about 20 - 25% of all cases of nephrotic syndrome.
Known causes include:
- Heroin use
- HIV
- Inherited genetic problems
- Obesity
- Reflux nephropathy (a condition in which urine flows backward from the bladder to the kidney)
- Sickle cell disease