Brugada syndrome risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Risk Factors: Agents and Scenarios that Provoke the Brugada Syndrome Pattern
The findings of Brugada syndrome are often concealed, but can be unmasked or modulated by a number of drugs and pathophysiological states including:
- Sodium channel blockers
- Fever
- Vagotonic agents that mimic sleep
- Tricyclic antidepressants
- Cocaine
- Propranolol intoxication
Risk Statification
- Patients with syncope and an abnormal Type 1 ECG are at higher risk
- Asymptomatic patients at risk can be identified
- Presence of spontaneous Type 1 ST-segment elevation
- Characteristics of the S wave
- Presence of late potentials
- Inducibility of VT/VF using PES.