Diastolic dysfunction laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Findings
Plasma brain natriuretic peptide (BNP) or N-terminal pro b-type natriuretic peptide (NT-proBNP) can be used to diagnose heart failure when diagnosis is unclear. The markers have been found to have lower levels in diastolic dysfunction when compared with systolic dysfunction[1]. Suggested partition values for diagnosis of DHF are BNP >100 pg/mL or NT-proBNP >300 pg/mL. In addition, BNP >100 pg/mL and NT-proBNP >300 pg/mL are independent predictors of adverse cardiovascular events in patients with heart failure with preserved left ventricular ejection fraction[2].
References
- ↑ Maisel AS, McCord J, Nowak RM, Hollander JE, Wu AH, Duc P; et al. (2003). "Bedside B-Type natriuretic peptide in the emergency diagnosis of heart failure with reduced or preserved ejection fraction. Results from the Breathing Not Properly Multinational Study". J Am Coll Cardiol. 41 (11): 2010–7. PMID 12798574.
- ↑ Grewal J, McKelvie RS, Persson H, Tait P, Carlsson J, Swedberg K; et al. (2008). "Usefulness of N-terminal pro-brain natriuretic Peptide and brain natriuretic peptide to predict cardiovascular outcomes in patients with heart failure and preserved left ventricular ejection fraction". Am J Cardiol. 102 (6): 733–7. doi:10.1016/j.amjcard.2008.04.048. PMID 18773998.