Mental disorder causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Causes
Numerous factors have been linked to the development of mental disorders. In many cases there is no single accepted or consistent cause. A common view is that disorders often result from genetic vulnerabilities combining with environmental stressors (Diathesis-stress model). An eclectic or pluralistic mix of models may be used to explain particular disorders. The primary paradigm of contemporary mainstream Western psychiatry is said to be the biopsychosocial (BPS) model - incorporating biological, psychological and social factors - although this may not be applied in practice. Biopsychiatry has tended to follow a biomedical model, focusing on "organic" or "hardware" pathology of the brain. Psychoanalytic theories have been popular but are now less so. Evolutionary psychology may be used as an overall explanatory theory. Attachment theory is another kind of evolutionary-psychological approach sometimes applied in the context for mental disorders. A distinction is sometimes made between a "medical model" or a "social model" of disorder and related disability.
Genetic studies have indicated that genes often play an important role in the development of mental disorders, via developmental pathways interacting with environmental factors. The reliable identification of connections between specific genes and specific categories of disorder has proven more difficult.
Environmental events surrounding pregnancy and birth have also been implicated. Traumatic brain injury may increase the risk of developing certain mental disorders. There have been some tentative inconsistent links found to certain viral infections, to substance misuse, and to general physical health.
Abnormal functioning of neurotransmitter systems has been implicated, including serotonin, norepinephrine, dopamine and glutamate systems. Differences have also been found in the size or activity of certain brains regions in some cases. Psychological mechanisms have also been implicated, such as cognitive and emotional processes, personality, temperament and coping style.
Social influences have been found to be important, including abuse, bullying and other negative or stressful life experiences. The specific risks and pathways to particular disorders are less clear, however. Aspects of the wider community have also been implicated, including employment problems, socioeconomic inequality, lack of social cohesion, problems linked to migration, and features of particular societies and cultures.
Causes in Alphabetical Order
- Abnormal behavior
- Abnormal functioning of neurotransmitter systems
- Angry outbursts
- Attention deficit
- Behavioral disorders
- Brachioradial pruritus
- Brain defects or injury
- Bullying
- Cannabis use
- Changing jobs or schools
- Chromosome 22q11.2 deletion syndrome
- Comorbid anxiety
- Developmental language disorder
- Difficulty delaying gratification
- Down syndrome (Trisomy 21)
- Duchenne muscular dystrophy (DMD)
- Dysfunctional family life
- Dysthymic disorder
- Ego-syntonic symptoms
- Emotional maltreatment
- Emotional neglect
- Emotional processes
- Environmental [stres[sors]]
- Exhibitionism
- Experiences in the womb (mother who was exposed to viruses, toxins, drugs or alcohol during pregnancy)
- Externalizing and blaming the world for their behaviors and feelings
- False perceptions (visual, auditory or olfactory)
- Feelings of inadequacy
- Financial problems
- Fragile X Syndrome (FMR1)
- Frequent mood swings
- Frotteurism
- Functional impairment (self-care, work, and interpersonal functioning)
- Gambling addiction
- Generalised anxiety disorder (GAD)
- Genetic vulnerabilities
- Global developmental delay/intellectual disability
- High risk sexual behavior
- Hyperactivity disorder (ADHD)
- Impulse control disorders
- Job loss
- Lack of social cohesion
- Landau-Kleffner syndrome (LKS)
- Language-based learning disability
- Learning disorders
- Lesch Nyhan syndrome
- Long-term opioid use
- Low self-esteem
- Migration
- Miscellaneous neurologic events
- Neuropsychiatric disorder
- Otalgia paresthetica
- Paraphilia
- Perinatal causes (hypoxia, infection, trauma and intracranial hemorrhage)
- Polysubstance use
- Poor nutrition
- Post traumatic disorder
- Postnatal causes (environmental toxins, psychosocial deprivation, malnutrition, intracranial infection, CNS malignancy)]]
- Postpartum psychosis
- Rett's disorder
- Schizotypal Personality Disorder
- Severe early deprivation/reactive attachment disorder
- Sexual Masochism
- Shared Psychotic Disorder
- Significant early loss
- Socioeconomic inequality
- Specific phobias
- Substance use disorder
- Substance-induced psychotic disorder
- Suicide attempts
- Traumatic event
- Undifferentiated Somatoform disorder
- Unemployment
- Unplanned pregnancy
- Voyeurism